Searchable abstracts of presentations at key conferences in oncology

oa0001p019 | (1) | PacRim7

Array comparative genomic hybridisation of familial prostate cancer tumours identifies a recurrent copy number gain on chr19p13.3 encompassing the EEF2 gene

FitzGerald LM , Raspin K , Marthick JR , Malley RC , Donovan S , Dickinson JL

In a bid to discover genomic features associated with prostate cancer (PrCa) development and progression, copy number variations (CNVs) have been studied in tumour samples. Early comparative genomic hybridisation (CGH) studies led to the identification of many chromosomal regions of loss and gain, with a small number of these shown to be consistent across studies and, significantly, some suggested to be associated with PrCa progression. More recently a small number of studies ...